The Puma Suit and Elements of Power's take on the F-22 issues.

Elements of Power goes over the issues with the F-22 in one of his blog posts...very informative stuff but what actually blew me away was his short talk about the Puma Suit.

Back during the development of the F-22 the USAF was aware of the altitudes at which the F-22 would be operating and had a decision to make.

Either wave the restrictions on the normal flight suit at those altitudes or develop a new pressure suit to help safeguard its pilots.  The USAF chose to roll the dice on new tech and it MIGHT be coming back to bite them.  Read his entire post but I wonder if it could be as simple as a pressure suit to solve the F-22's woes.